Miller underwent exploratory surgery in Texas on Tuesday.
Von Miller of the Buffalo Bills was initially placed on injured reserve last Thursday before the game against the New England Patriots.
Last week, Miller needed a knee scope as the swelling went down and the team began searching for different opinions.
Unfortunately for the Buffalo Bills, it was announced that Miller would require ACL surgery, leaving him out for the rest of the season.
There was hope that he’d be able to return this season but those hopes are out of the window.
Bills General Manager Brandon Beane said: “I knew Monday night that this was a real potential, you know, crossing our fingers. We were hopeful that it was a scope to clean the meniscus up and any scar tissue in there.
“But unfortunately, when [Dr. Cooper] went in there yesterday -- he did the surgery sometime yesterday afternoon -- when he went in there yesterday afternoon, he decided that it would not be stable enough, it would not hold up, and that a full repair was needed.”
At the moment, the Bills are at the top of the AFC East and the main reason for this is their impressive defense. Without Miller in the lineup, however, they could be in trouble.
Head Coach Sean McDermott said: “Unfortunate situation, for Von, obviously, and our team. Care for him, obviously, like we would any player.
“We know how much this means to him in terms of playing and being with the team, so we look forward to getting him back, obviously off the field for the rest of the season and his leadership, and we're certainly thinking about him as he recovers here.”